In vitro characterization of an osteoinductive biphasic calcium phosphate in combination with recombinant BMP2
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چکیده
منابع مشابه
In vitro characterization of an osteoinductive biphasic calcium phosphate in combination with recombinant BMP2
BACKGROUND The repair of alveolar bone defects with growth factors and bone grafting materials has played a pivotal role in modern dentistry. Recombinant human bone morphogenetic protein-2 (rhBMP2), an osteoinductive growth factor capable of cell recruitment and differentiation towards the osteoblast lineage, has been utilized in combination with various biomaterials to further enhance new bone...
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The aim of this study was to evaluate the synergistic effect of platelet-rich plasma (PRP) and recombinant human bone morphogenic protein (BMP)-2 on accelerated osteogenesis of hydroxyapatite/β-tricalcium phosphate mixture and biphasic calcium phosphate (BCP) in mastoid obliteration. To the best of our knowledge, there have been no studies reporting the enhancing effects of BCP, combined with B...
متن کاملAn evaluation of hydroxyapatite and biphasic calcium phosphate in combination with Pluronic F127 and BMP on bone repair.
Calcium phosphates like hydroxyapatite (HA), beta-tricalcium phosphate (beta-TCP), and their mixtures (biphasic calcium phosphates; BCP) are used clinically to repair bone defects. These materials can be difficult to handle and have no inherent biological activity. Handling properties of other bone substitute materials have been improved by combining them with an inert carrier such as Pluronic ...
متن کاملNanoscale surface characterization of biphasic calcium phosphate, with comparisons to calcium hydroxyapatite and β-tricalcium phosphate bioceramics.
OBJECTIVES It is our aim to understand the mechanisms that make calcium phosphates, such as bioactive calcium hydroxyapatite (HA), and biphasic calcium (BCP) and β-tricalcium (β-TCP) phosphates, desirable for a variety of biological applications, such as the filling of bone defects. METHODS Here, we have characterized these materials by X-ray photoelectron spectroscopy (XPS), X-ray diffractio...
متن کاملSedimentation Study of Biphasic Calcium Phosphate Particles
Injectable calcium phosphate (CaP) biomaterial is considered as an injectable bone substitute (IBS). It was developed to minimize invasive surgery in various applications in orthopedic and dental surgery. The IBS considered of a polymer solution mixed with biphasic calcium phosphate (BCP) ceramic particles. Two particle sizes of BCP (40-80 and 80-200μm) were used and the weight ratio was 40%. T...
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ژورنال
عنوان ژورنال: BMC Oral Health
سال: 2016
ISSN: 1472-6831
DOI: 10.1186/s12903-016-0263-3